Beginning at the border of Orleans and St. Bernard Parishes and stretching 29 miles along Louisiana Hwy 46, the San Bernardo National Scenic Byway traverses St. Bernard Parish along the Mississippi River to the fishing villages of Yscloskey and Delacroix Island. Many of St. Bernard's major attractions are located along the byway including the Old Arabi Historic Districts, Chalmette Battlefield & National Cemetery, Docville Oaks and Farm, and the Islenos Museum & Village Complex.

Along the drive, visitors will view historic plantation homes, a historic courthouse, the St. Bernard Cemetery, one of the oldest burial grounds in Louisiana, and Contreras Plantation site the birthplace of P.G.T. Beauregard. Those traveling the byway will have their choice of many of St. Bernard's famous eateries, or stop at a roadside stand for fresh produce and seafood.

Be sure to pick up a St. Bernard Where Map from the Visitor Center or your local hotel to guide you along the scenic byway.